時間を計る脳(時間とリズム-知覚・感性・生理-,2009年度第1回フォーラム)
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概要
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We unconsciously sense passage of time, and generate regular recurrent trains of movements like vocalization, walking or respiration, without an effort. This ability of temporal perception must be traced down to the loci in the human brain. Although still premature, the research on this line is indicating that at least three distinct modes are present to sense the time passage in the brain. Very long time, like an event in childhood is dealt with mechanisms involving memory consolidation, retrieval and association. The Hippocampus and orbitofrontal cortex are implicated in this mode of time perception. Time of the day sense and its underlying clock has been well delineated recently by the molecular biological technique. The circadian pacemaker is located in the Suprachiasmatic nucleus of the hypothalamus and driven by the feedback loop at the gene and protein level. Third mode of time sensing is the generation of short interval of time. These second to minute rhythms are in part taken care of in the nucleus of the basal forebrain such as the Striatum and Caudate nucleus.
- 2010-03-31