＜Symposium V＞New avenues in the pathogenesis of subarachnoid hemorrhage

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概要

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• Background ̶Subarachnoid hemorrhage （SAH） remains a disease without any definitive treatmentoptions. Research, to date, has concentrated on the pathophysiology of vasospasm. Recent evidence supports theconcept of Early Brain Injury （EBI）, a phenomena which may help to explain the complex pathophysiology seen inpatients after a SAH. Summary ̶EBI aims to describe the pathophysiological events that occur in the brain withinthe fi rst seventy two hours after a SAH, before the onset of vasospasm. A number of pathways have been identifi edwhich may play a role in the etiology of EBI. This review provides a brief synopsis of EBI and its implications for thefuture. Conclusions ̶EBI may represent a key event in the development of both vasospasm and Delayed IschemicNeurological Deficit （DIND） after subarachnoid hemorrhage. Additional studies are required to determine thepathophysiology of EBI and to examine its role as a possible precursor to both vasospasm and DIND.

著者

• Cahill Julian

  Department of Physiology, Loma Linda University Medical School

• Zhang John

  Department of Physiology, Loma Linda University Medical School

• Zhang John

  Department Of Physiology Loma Linda University Medical School

• Zhang John

  Department Of Neurosurgery University Of Mississippi Medical Center

• Cahill Julian

  Department Of Physiology Loma Linda University Medical School

関連論文

• ＜Symposium V＞New avenues in the pathogenesis of subarachnoid hemorrhage
• Role of Apoptosis in Cerebral Vasospasm after Subarachnoid Hemorrhage

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