Involvement of Taurine in the Skeletal Muscle on Exercise
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概要
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Taurine, a non-protein sulfur contain amino acid-like compound, has been reported to play the physiological and pharmacological roles in the various tissues. Taurine affects on the properties of skeletal muscles via the homeostasis of Ca^<2+>, stabilization of the intracellular membrane, modulation of nerve excitement, and consequently, enhances exercise performances. The previous studies and ours have shown the effectiveness of oral taurine administration on exercise ability by the inhibition of loss of muscular taurine concentration. These findings have supported by the evidences that the significant depletion of taurine in the skeletal muscles induced the marked low of physical properties with morphological abnormalities in this tissue in the taurine transporter knockout mice. Thus, the maintenance of taurine in the skeletal muscles is important factor for physical activities.
著者
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MIYAZAKI Teruo
Department of Development for Community Medicine, Tokyo Medical University
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Miyazaki Teruo
Department Of Development For Community Medicine Tokyo Medical University
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