イヌにおける気腹圧と腎機能に関する研究

概要

論文の詳細を見る
It has been reported that during surgery under peritoneoscopy using pneumoperitoneal techniques, blood flow in the kidney decreases accompanied with a rise in pneumoperitoneal pressure. Therefore, I studied the effect of pneumoperitoneal pressure on renal function in dogs. Group I included 10 dogs with normal renal function and group II, 10 dogs who had undergone unilateral nephrectomy. The pneumoperitoneal pressure was limited to four levels, i.e., 5, 7, 10 and 15 mmHg. Changes in renal function after the removal of the pneumoperitoneum were also stuided. The renal function was evaluated by determination of the glomerular filtration rate (GFR) using the parameters of serum renin activity and angiotensin II. The results showed a decrease in the values of GFR accompanying the rise of pneumoperitoneal pressure in both groups. In group I, the values of GFR recovered early to the baseline values after the removal of the pneumoperitoneum, but in group II the recover was delayed. Moreover, the levels of renin activity and angiotensin II rose, accompanying the rise in pneumoperitoneal pressure, then after the removal of the pressure they were shown to decrease at an early stage in group I, while they remained high in group II.
東京女子医科大学の論文
1996-12-25