ROSETTE-FORMATION OF HUMAN B-LYMPHOCYTES WITH MOUSE ERYTHROCYTES, AND ITS ULTRASTRUCTURAL SURFACE ARCHITECTURE

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概要

• 論文の詳細を見る

• The experiments were designed to prove that rosette-formation with mouse red blood cells (MRBC) is a specific property to human B-lymphocytes, and that the lymphosytes with the receptors to MRBC have a characteristic surface architecture when observed by scanning electron microscopy (SEM). A small number of peripheral lymphocytes from healthy individuals formed rosettes with MRBC (6.6±2.7%). The rosette-forming cells were enriched up to 19.5±4.6% by eliminating the most parts of T-lymphosytes, and T-lymphosytes-enriched fraction formed rosettes with MRBC in negligible value (0.2±0.2%). The lymphocytes from 2 cases of chronic lymphocytic leukemia (CLL) which had been identified as B-lymphocytes in origin showed MRBC-rosette-formation in 89.3% and 59.8%, respectively. It would be threfore concluded that MRBC-rosette-formation is the property of human B-lymphocyte subset. Normal and leukemic lymphocytes which have relatively smooth cell-surface with a few short microvilli, resembling T-lymphocytes, are characteristic to the B-lymphocytes with the receptors to MRBC.

• 名古屋市立大学の論文
• 1982-07-30

著者

• 正岡 昭

  Department Of Blood Transfusion Nagoya City University Hospital

• 松本 美富士

  Department Of Blood Transfusion Nagoya City University Hospital

• 渡 仲三

  First Department Of Anatomy Nagoya City University Medical School

• 堀田 康明

  First Department of Anatomy, Nagoya City University Medical School

関連論文

• ROSETTE-FORMATION OF HUMAN B-LYMPHOCYTES WITH MOUSE ERYTHROCYTES, AND ITS ULTRASTRUCTURAL SURFACE ARCHITECTURE

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