PURE WATER INTOXICATION IN A CHRONIC SCHIZOPHRENIC PATIENT
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概要
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A case history is presented for a schizophrenic patient who drank water in excess amounts and subsequently developed cardiopulmonary arrest due to water intoxication. The patient survived by resuscitation. The diagnosis was pure water intoxication, occurring with supression of antidiuretic hormone (ADH) release despite preservation of maximal renal diluting capacity. The low level of ADH in serum confirmed directly by radioimmunoassay is first documented in pure water intoxication. The treatment (except for psychiatric aspects) consisted of the restoration of plasma osmolarity: that is, water excess was treated both by fluid restriction and by infusion of hypertonic electrolytes. The incidence of water intoxication seems to be underestimated. Therefore, by the routine measurement of sodium level, when hyponatremia is documented and polydipsia is suspected, water restriction is necessary as a preventive measure. The correlation of water intoxication and psychotic patients is discussed.
- 名古屋市立大学の論文
- 1984-10-29
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