血液透析療法と臨床免疫学的研究 : とくに体液性免疫と細胞性免疫の変動を中心として

概要

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It is considered that immunity relates to infection in hemodialyzed patients. In the humoral immunity seruro-IgA level in hemodialyzed patients has shown decrease with dialyzed term. Then in the cell-mediated immunity we compared hemodialyzed patients with normal individuals, chronic nephrititis patients in adults and infants of nephrititis by means of the tuberculin reaction. The consequence was that the cell-mediated immunity in hemodialyzed patients has shown decrease more than that of these three groups of comparison, and that the tuberculin reaction has changed into negative in most of hemodialyzed patients who were treated with hemofiltration more than three years, and that the cell-mediated immunity had relation to PHA skin reaction. The correlation between T cell and B cell in vitro and dialyzed term, however, has not been demonstrated, that is to say, dialyzed term had no effect on T cell and B cell in vitro. Therefore it seems appropriate to consider that immunity which relates to infection is more significant in vivo reaction than in vitro reaction.
神戸大学の論文