心拍位相同調法による冠動脈造影法の研究
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概要
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(1) This report is aimed to increase the safety and reliability of coronary arteriography in order to determine the diagnosis and indication for operation of coronary artery diseases. (2) Experimental coronary arteriograms by the apparatus timed the fractional phase of the cardiac cycle were carried out in 95 mongrel dog's, and several factors to influence adequate arteriograms have been investigated. The catheter being inserted to the root of the aorta was connected this equipment, radio-opaque contrast medium was injected into the coronary arteries, and x-ray exposure was made automatically. It was found that the coronary flow would be maximum filling in the early cardiac diastole and radio-opaque contrast medium require two cardiac cycles to reach the distal coronary branches. In relation to the aortic flow, the contrast material was diluted most if it was injected in the early systole and poorly if it was in the late systole as the diastole. The ideal time for x-ray exposure in the late diastole was derived from analysis of the electrokymograms. (3) In review of these investigations the contrast material was injected from the late systole to the early diastole in order to demonstrate the proximal regions of coronary arteries, and timing of x-ray exposure was present within the first cardiac cycle or late diastole in the subsequent cycle. To visualize whole branches of coronary arteries the injection of the opaque medium and exposure were done in two cardiac cycles from late systole. Dossages 0.2 to 0.5ml. per kg the medium were employed. (4) This method provides us more effective arteriograms than cardiac arrest method with acetylcholine. In addition it is more reliable and consistent in EGG or blood pressure and amount of injection is enough under the half. (5) As clinical application, 9 cases of cardiac diseases were performed diagnostic arteriography. Adequate left coronary arteries visualization was obtained and no complications were occurred in all patients.
- 千葉大学の論文
- 1965-05-28
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