慢性胃炎に関する組織病理学的研究
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概要
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A dynamic histopathological study of the gastric mucosa in chronic gastritis, based on the findings of 50 surgically resected stomachs, is presented. The mode of development of chronic gastritis is characterized by 1) hyperplastic inflammatory processes in the earlier stage, 2) hyperplastic-atrophic processes in the subsequent stage, and 3) atrophy in the terminal stage. It is worthy of note that the inflammatory processes take place in the gastric mucosa as a whole consisted of the overlying as well as glandular epithelium and the interstitial tissue including blood capillaries. It was ascerained by the examination of longitudinal sections of the resected stomachs from the oral end through pyloric end that the processes of chronic gastritis initiated by hyperplasia and resulting in atrophy first appear in the pars pylorica and extend gradually from here to the corpus. Chronic gastritis is characterized by serous exudation followed by leukocytic (including eosinophilic) infiltrations, plasma cellular reaction, and formation of lymph follicles, and ends in atrophy of the gastric mucosa with fibrosis and sclerosis. During the course, atrophy and disappearance of the glandular tissue and occasional atypical proliferation of the epithelium following disorganization of the mucosal architecture were noticed.
- 千葉大学の論文
- 1963-11-28
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