Banti症候群の臨床的研究

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86 cases of Banti's Sydrome seen in our clinic from 1925 to 1961 were studied on their clinical and laboratory findings with special attention to hematological changes and hepatic functions, and in addition the changes of these in the cases with splenectomy were also investigated over 2 years after the operation. The incidence of Banti's Syndrome was 0.026% of all patients in our clinic, and most of the cases were females, 4 th as numerous as males, and seen mostly in the age between 35 to 50 years. In the complaints and signs, those caused by anemia were most frequently seen, the next was abdominal ones and the liver was palpated in 86% of all cases. Hematemesis was seen in 16.2%. The hematological studies revealed pancytopenia. The anemia was of microcytic hypochromic type accompanied by low serum iron lebel, the ^<51>Cr tagged red cell survival time was shortened slightly or moderately and hemorrhagic diathesis was also found in many cases. All of these findings indicate as the causes of anemia, iron deficiency, increased erythrocyte destruction and blood lost due to hemorrhage. In many cases, the bone marrow showed normal or increased erythroblast and the. sign of inhibited maturation of granulocytes. Hypoplasia was rarely seen. The liver function testes showed abnormal in most of cases ; slightly or moderately increased serum bilirubin, direkt or indirekt type, prolonged BSP retention, and abnormal serum protein reoction, but the serum transominase and alkaline phosphatase were mostly normal. The investigations of serum protein by the method of paper electrophoresis showed hyoproteinemia, reduction of albumin and increase in γ globulin. Splenectomy improved these hematological abnormalities, and this improvement retained over 2 years so far as our observations were concerned. However the liver functions did not necessary showed better and occasionally revealed worse after the operation.
千葉大学の論文
1963-01-28

Banti症候群の臨床的研究

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