反覆刺激法に基く脊髄反射機能の誘発筋電図学的研究
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Magladery (1950), applying an electrical stimulus percutaneously to a peripheral nerve (N. Tibialis), transmitted monosynaptic centaipetal impulses over the arc of spinal reflex and elicited excitement of the muscle supplied by that nerve. He termed the action potential thus recorded the H wave, and heed that it indicated a reflex action of the spine. In the belief that examination of various patterns of the H wave to be produced by applying repeated electrical stimulus in different cycles is the best method for selective study of excitability of the spine synapse, the author carried out a series of clinical and fundamental experiments. Excitability of the spinal synapse was studied by this method in the following three groups: normal individuals, individuals in whom the upper central neuron was examined and patients with disturbance of examined spinal center. It was shown that excitability of the spinal synapse in each group was manifested in a characteristic manner, and that variations in pattern were marked enough to distinguish one form the other. Experiments were also conducted to study the mechanism of involvement of the function of spinal reflex by anesthesia. General anesthesia was induced by the administration of ether and Thiobal (thiopental sodium) before application of electrical stimulus. After transmitting impulses chiefly by means of repeated stimulation method and evaluating various factors affecting the apinal reflex arc, the author found that the relation between the depth of anesthesia and excitability under ether anesthesia differed in pattern from that under Thiobal anesthesia.
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