甲状腺疾患に於ける甲状腺刺激ホルモン試験(TSH test)の臨床的応用に関する研究

概要

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T. S. H. test is a useful method for understanding the dynamics of pituitary-thyroid axis. In this study, changes of the thyroid function by the administration of T. S. H. were investigated of I uptake rate and serum protein bod iodine in the normal and the suffered people from thyroid diseases. The results are summarized as follows. (1) From the results of T. S. H. test in the normal, simple goiter, goiter II, hypothroidism, and subacute thyroiditis, these facts were derived that goiter II is to be included inthe cate ory of simple goiter in the mode of response to T. S. H., hypothyroidism be divided into two types, primary and pituitary, and subacute thyroiditis shows a relatively early recovery of the thyroid follicular cell function. (2) From the results of T. S. H. test in Graeves disease and toxic goiter, especially following the course of therapies, it was found that the both diseases are to be differentiated one another. And following the improvement of the diseases, they become respond similarly each other in T. S. H. test, further do they show a response as simple goiter when they are cured. So, it is considered that T. S. H. test is applicable to determination of the recovery from hyperthyroidism.
千葉大学の論文