胆嚢剔出後の脂肪の消化吸収
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概要
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It is the bile that plays the most important part in digestion and absorption of fat. The gallbladder concerns in the storage, condensation and outflow of the bile into the duodenum. By using I^<131> labeled peanut oil, the author conducted studies on how surgical removal of the gallbladder would affect digestion and aborption of fat. Liver function tests and cholecystocholangiography in combination with percutaneous injection of contrast medium were also performed. Evaluation of the results of these tests, as well as the results of operation, led to the following conclusions : (1) Animal experiments showed that digestion and absorption of fat following surgical removal of normally functioning gallbladder returned to more or less normal levels in about 3 months. This would indicate that, so far as digestion and absorption of fat is concerned, the gallbladder is not necessarily indispensable. (2) Disturbed outflow of the bile due to stenosis of the bile ducts and the change in its constituents ascribable to impairment of liver function caused by disturbed outflow of the bile may have a bearing on digestion and absorption of fat. Cholecystectomy should be performed before morbid changes have spread to the bile ducts and liver. (3) When digestion and absorption of fat has returned to normal levels following cholecystectomy, it would be unnecessary to limit the amount of fat to be given to patients. In view of the results of animal experiments, it would seem that digestion and absorption of fat may become normal in about 3 months following cholecystectomy. If tests for digestion and absorption of fat are normal at that time, a patient may be placed on a regular diet thereafter.
- 千葉大学の論文
- 1958-11-28