血漿蛋白像より観たる血清反応の臨床的研究
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概要
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The three serum reaction tests-Takada's reaction, cobalt reaction and cadmium reaction-were performed in patients with diseases of the liver and bile duct, and the results of tests were correlated with the plasma protein pattern based on clinical as well as experimental findings. It was revealed that many of the patients with hepatitis and cirrhosis of the liver were positive for Takada's and cobalt reactions, and that an increase in the amount of gamma globulin was the main factor in the phenomenon and a decrease in the amount of albumin expedited it. Al fa and beta globulins, too, had an influence on the two reactions, which did not always occur in the same patient. Heterogenicity of the protein concerned in the reaction was experimentally established in Takada's reaction, but not in cobalt reaction. Unlike the two reactions described above, cadmium reaction had high positive rate among patients with malignant tumor, and low positive rate among patients with hepatitis and cirrhosis of the liver. It was observed that al fa and beta glubulins expedited, and albumin and gamma globulin checked, the reaction. However, the fact that the positive rate of this reaction had little to do with these protein fractions would indicate that, besides protein, some other factor might concern in the reaction. The results of the present experiments would attest to the significance of the three serum reaction tests in the diagnosis of the diseases of the liver and bile duct.
- 千葉大学の論文
- 1958-05-28
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関連論文
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