乳幼児に見られるおしめかぶれの臨床的研究 : 1 臨床的観察

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For the purpose of contributing to the treatment and prevention of diaper rash which often afflicts babies, the author carried out a study on its clinical pictures as well as its cause. (1) Investigations on whether diet and disposition are factors having some share in the development of diaper rash have revealed that diet has nothing to do with its development, while it occurs more often in babies with exudative diathesis (61% in the present study) than in babies of any other type and shows a tendency to aggravation. (2) It was found clinically that there were two varieties of diaper rash, each having a distinctive clinical picture : one is a dermatitis due to the ammonia formed in diapers wet with the urine, and the other is a dermatitis caused by the presence of stools, especially watery stools in diaper. (3) Bacteriologic examinations of these two types of diaper rash have revealed that, in cases of a dermatitis due to ammonia, large numbers of microorganisms of Bac. ammoniagenes, the genus Sarcina and the genus Micrococcus having a strong urea decomposing ability are found in wet diapers rather than in stools. It would seem that the ammonia formed as a result of the decomposition of urea by these microgroanisms in wet diapers causes the development of a dermatitis in babies. In cases of a dermatitis due to the presence of watery stools in diapers, lowering in hydrogen ion concentrations of stools and multiplication in the intestines of microorganisms of the genus Candida and the genus Streptococcus, especially enterococcus, that are gram positive, have been proved. This would in dicate that the number of microorganisms producing ferment in the intestines has increased, and that diarrhea due to intestinal fermentation of carbohydrates by these organisms causes a dermatitis.
千葉大学の論文
1957-03-28

著者

池田公明
千葉大学医学部小児科教室

乳幼児に見られるおしめかぶれの臨床的研究 : 1 臨床的観察

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