肝,腎及び内分泌疾患に於ける副腎皮質機能の臨牀的研究
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Based on the results obtained in testing the rate of decrease of the eosinophils, and in measuring the levels of 17 K S as well as the rate of increase of the ratio U.A./C. in the urine, the author carried out researches on the functions of the adrenal cortex in disorders of the liver, kidneys and other endocrinous organs, investigating into its actions in different diseases and at different stages of particular diseases. The results of the investigations are summarized as follows: (1) Low levels of 17 K S excreted in the urine in hepatic disorder arising from disturbances of the hepatic functions. It might be associated with antidotal function of the liver. (2) Low levels of 17 K S detected in the urine in kidney disorder seem to be attributed to the disturbances of excreting function of the kidneys. In acute nephritis, it might not be due to deficient secretion of corticoid, while, in chronic nephritis, it might be associated with insufficiency of the adrenals. In the active stage of nephrosis, insufficiency of the pituitary body adrenal gland system was observed. (3) In diabetes, the levels of 17 K S excreted in the urine were more or less in the normal range. (4) In Simmond's syndrome, marked lowering in the functions of the pituitary body adrenal gland system was observed. Scleroderma mightbe due to multiple endocrinous insufficiency; it might be closely associated with the functions of the pituitary body adrenal gland system.
- 千葉大学の論文
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- 肝,腎及び内分泌疾患に於ける副腎皮質機能の臨牀的研究