急性出血及びその処置に関する実験的研究 : 特に血液ガスについて
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概要
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The author examined the influence of acute hemorrhage on the values of blood constituents, especially on the blood gas, and undertook investigations of the efficacy of the administration of oxygen and transfusion of whole blood as its remedy. Experiments were carried out in the rabbit. 1) Acute hemorrhage has diminished the values of blood constituents, and the blood gas has been caused to represent the symptoms of acute anoxemia. The larger the quantity of bleeding the more marked were these changes, with the peak of symptoms having been reached in about 2 days after bleeding. An improvement of these symptoms took 10-14 days and 2-3 weeks in the bleeding of medium degree (10 cc per Kg. of body weight) and of large degree (20 cc per Kg. body weight), respectively. 2) The administration of oxygen by means of closed circuit anesthesia has shown remarkable effect in the treatment of acute hemorrhage; anemic symptoms were slight and the total disappearance of the symptoms of anoxemia was observed during the ad ministration of oxygen. However, anoxemia has occurred again when the administration of oxygen was discontinued, and the ultimate recovery was not expedited. 3) The transfusion of the same quantity of whole blood as was lost in bleeding, in combination with the administration of oxygen, has brought about almost the total disappearance of anemic symptoms. Under this treatment, the symptoms of anoxemia have been greatly improved even after the discontinuance of the administration of oxygen, and consequently the ultimate recovery was expedited. In the opinion of the author, wholesale transfusion achieves better results than other methods.
- 千葉大学の論文
- 1954-09-28