移植自家骨片の運命に関する実験的研究

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I have made an investigation both histological and radiological with references to the processes of change some pieces of rabbit's tibia and rib taken from underneath the periosteum undergo, when transplanted into the muscle, subfascial, liver, spleen, omentum major, granulation-tissue, bone defects and callus. The bones gradually fall into the state of necrosis with the result that connectivetissue and osteocrast absorb them. On the other hand, nearly at the same time, osteoblastbecomes aictfve apposition of osteoid-tissue and is observed chiefiy in places like the marrow, endosteum, resorption-lacuna. The absorption always goes ahead of apposition, and in a final stage the bones remain in bits enclosed in newly-formed osteoid-tissue, otherwise only the newly-formed osteoid-tissue remains. As for the marrow, it is, once' going through the process of necrosis, restored with blood supply to its former state and will survive long. In the above stated processes, there is no fundamental difference with regard to beds of plantation, though the change is most conspicuous in the spleen, granulation-tissue, omentum major. In case of the bones transplanted in bone beds split ones show the most remarkable change.
千葉大学の論文