根管洗浄液としてのアルカリイオン水の応用 : 細胞毒性と有機質溶出試験

概要

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This study was carried out to examine the possibility of using alkali-ion water for root canal irrigation. The biocompatibility of alkali-ion water was tested by assessing its effect on mitogenic activity of cultured human pulp fibroblast cells. In addition, a cytotoxicity assay was also conducted using rat lymphocytes, which were more easily damaged than human pulp fibroblast cells. In addition, the organic material-dissolving capacity of alkali-ion water was evaluated. The numbers of living cells (rat lymphocytes and human pulp fibroblast cells) did not significantly differ between the control (physiological saline) group and the alkali-ion water group. Furthermore, cytotoxicity experiments showed no significant differences between the control and alkali-ion water groups. However, alkali-ion water showed significantly increased organic materialdissolving capacity compared with the control. These results indicate that the alkali-ion water is sufficiently safe and useful for clinical application of root canal treatment.
特定非営利活動法人日本歯科保存学会の論文
2006-12-31