Expression of SART-1 mRNA in Canine Squamous Cell Carcinomas(Surgery)
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概要
- 論文の詳細を見る
SART-1, a squamous cell carcinoma (SCC) antigen recognized by cytotoxic T lymphocytes, has been useful in human cancer therapy. The SART-1_<259> peptide is a potential candidate for vaccine. The present study examined an orthologue of the mRNA coding this peptide in canine SCCs. Specimens were obtained from seven canine patients with SCC, and the mRNA was isolated from the samples. The SART-1 and beta-actin genes were amplified by reverse-transcription polymerase chain reaction, using the isolated mRNA as a template. Canine SART-1 was amplified in six of the seven specimens, while beta-actin was detected in all the samples. In dogs, carcinomas expressing SART-1 could be a target for cytotoxic T lymphocyte mediated immunotherapy.
- 社団法人日本獣医学会の論文
- 2008-12-25
著者
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Yoshida Yukari
College Of Veterinary Medicine Nippon Jui-seimeikagaku University
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Taniguchi A
College Of Veterinary Medicine Nippon Jui-seimeikagaku University
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TAKAISHI Yumi
College of Veterinary Medicine, Nippon Jui-Seimeikagaku University
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NAKAGAKI Kazuhide
College of Veterinary Medicine, Nippon Jui-Seimeikagaku University
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FUJITA Michio
College of Veterinary Medicine, Nippon Jui-Seimeikagaku University
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TANIGUCHI Akiko
College of Veterinary Medicine, Nippon Jui-Seimeikagaku University
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ORIMA Hiromitsu
College of Veterinary Medicine, Nippon Jui-Seimeikagaku University
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Takaishi Yumi
College Of Veterinary Medicine Nippon Jui-seimeikagaku University
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Fujita Michio
College Of Veterinary Medicine Nippon Jui-seimeikagaku University
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Orima Hiromitsu
College Of Veterinary Medicine Nippon Jui-seimeikagaku University
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Orima Hiromitsu
Department Of Veterinary Radiology Nippon Veterinary And Life Science University
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Nakagaki Kazuhide
Nippon Jui‐seimeikagaku Univ. Tokyo
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Nakagaki Kazuhide
College Of Veterinary Medicine Nippon Jui-seimeikagaku University
関連論文
- Expression of SART-1 mRNA in Canine Squamous Cell Carcinomas(Surgery)
- Measurement of Brain Trace Elements in a Dog with a Portosystemic Shunt : Relation between Hyperintensity on T1-Weighted Magnetic Resonance Images in Lentiform Nuclei and Brain Trace Elements(Surgery)
- 猫免疫不全ウイルス感染無症状猫におけるTリンパ球依存性および非依存性抗原に対する抗体産生能(短報)〔英文〕
- Measurement of Brain Trace Elements in a Dog with a Portosystemic Shunt : Relation between Hyperintensity on T1-Weighted Magnetic Resonance Images in Lentiform Nuclei and Brain Trace Elements
- Expression of SART-1 mRNA in Canine Squamous Cell Carcinomas
- Intranasal Hemangiosarcoma in a Dog