The role of lipid peroxidation in the genesis of vasospasm secondary to subarachnoid hemorrhage.

スポンサーリンク

概要

• 論文の詳細を見る

• The aim of this study is to find out the possible trigger role of lipid peroxidation in vasospasm. Haemoglobin-free washed erythrocyte membranes (erythrocyte ghost) corresponding to 2.5 mg membrane protein was mixed with 0.5 umol NADPH 3 umol ADP, 4 umol ferrous sulphate and injected into the cisterna magna of cats to stimulate lipid peroxidation in vivo (Group 1). The second group was injected lml/kg whole blood and the control group 1 ml/kg saline. Angiographic studies revealed significant vasospasm in five cats in group 1. Severe vasospasm was seen in six cats in group 2. A significant increase in lipid peroxidation was observed in groups 1 and 2, compared to the control group. These results may suggest that free radical products may play an important role in the complex genesis of vasospasm in subarachnoid haemorrhage.

• 神戸大学の論文

著者

• Benli K

  Department Of Neurosurgery Hacettepe University School Of Medicine

• Bolay H

  Department of Neurosurgery, Hacettepe University School of Medicine

• Caner H

  Department of Neurosurgery, Hacettepe University School of Medicine

• Orugkaptan H

  Department of Neurosurgery, Hacettepe University School of Medicine

• Kiling K

  Department of Neurosurgery, Hacettepe University School of Medicine

• Senaati S

  Department of Neurosurgery, Hacettepe University School of Medicine

• Ayhan A

  Department of Neurosurgery, Hacettepe University School of Medicine

関連論文

• The role of lipid peroxidation in the genesis of vasospasm secondary to subarachnoid hemorrhage.

スポンサーリンク