In Vitro Antioxidant Activity of Enicostemma axillare

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概要

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• Four successive extracts of the whole plant of Enicostemma axillare (E. axillare), were examined for in vitro antioxidant activity using nine different methods. In the 2, 2'-azino-bis (3-ethylbenzo-thiazoline-6-sulfonic acid) diammonium salt (ABTS) method, all the four extracts of E. axillare showed potent antioxidant activity with IC_<50> values ranging from 13.26 to 24.36μg/ml. The chloroform extract has shown potent antioxidant activity in H_2O_2, nitric oxide, and hydroxyl radical using the deoxyribose and lipid peroxidation methods, with IC_5O values of 16.99±0.38, 60.66±0.30, 25.06±0.12, and 94.66±2.40μg/ml, respectively. Potent activity was also observed for the petroleum ether extract with the deoxyribose, p-nitroso dimethyl aniline (p-NDA), and H_2O_2 methods and for the ethyl acetate extract with the H_2O_2 and nitric oxide methods. All extracts showed moderate total antioxidant capacity using the phosphomolybdenum method. The activity was not correlated with the total phenol content of the extracts.

• 2008-10-01

著者

• Bhojraj Suresh

  インド

• Vaijanathappa Jaishree

  Department of Pharmaceutical Chemistry, JSS College of Pharmacy

• Badami Shrishailappa

  Department of Pharmaceutical Chemistry, JSS College of Pharmacy

• Bhojraj Suresh

  Department of Pharmaceutical Chemistry, JSS College of Pharmacy

• Badami Shrishailappa

  インド

• Badami Shrishailappa

  Department Of Chemistry Gulbarga University

• Vaijanathappa Jaishree

  Department Of Pharmaceutical Chemistry Jss College Of Pharmacy

• Bhojraj Suresh

  Department Of Pharmaceutical Chemistry J. S. S. College Of Pharmacy

関連論文

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