Investigations of Saccharothrix algeriensis Growth on Synthetic Media(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
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概要
- 論文の詳細を見る
Development of bacterial resistance to antibiotics has lead to investigations of rare bacteria, which produce new bioactive molecules. Saccharothrix algriensis has been isolated from the desert Maghreb. It produces dithiolopyrrolones, some of which were newly identified. In order to optimize and control production of dithiolopyrrolones, investigation regarding microorganism metabolism was required. Growth on semisynthetic medium containing 2g・t^<-1> of yeast extract was complicated because it was performed on several substrates. Moreover, because development of this bacterium on minimum medium was difficult, its composition was optimized by screening of different compounds led by yeast extract. Uracil added to the minimum medium allowed a maximum biomass production of 1.35g・l^<-1> compared to 0.32g・l^<-1> without uracil. Moreover, nonpolar amino acids and trace metal elements stimulated Saccharothrix algeriensis growth.
- 2008-08-25
著者
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Lebrihi Ahmed
Universite De Toulouse Laboratoire De Genie Chimique Ecole National Superieure Agronomique De Toulou
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Strub Caroline
Universite de Toulouse, Laboratoire de Genie Chimique UMR CNRS-INPT 5503, Institut National Polytech
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Brandam Cedric
Universite de Toulouse, Laboratoire de Genie Chimique UMR CNRS-INPT 5503, Institut National Polytech
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Meyer Xuan
Universite de Toulouse, Laboratoire de Genie Chimique UMR CNRS-INPT 5503, Institut National Polytech
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Strub Caroline
Universite De Toulouse Laboratoire De Genie Chimique Umr Cnrs-inpt 5503 Institut National Polytechni
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Brandam Cedric
Universite De Toulouse Laboratoire De Genie Chimique Umr Cnrs-inpt 5503 Institut National Polytechni
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Meyer Xuan
Universite De Toulouse Laboratoire De Genie Chimique Umr Cnrs-inpt 5503 Institut National Polytechni
関連論文
- Investigations of Saccharothrix algeriensis Growth on Synthetic Media(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
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