Synthesis of Novel Salidroside Esters by Lipase-Mediated Acylation with Various Functional Acyl Groups(BIOCHEMICAL ENGINEERING)
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概要
- 論文の詳細を見る
Salidroside, a natural glycoside, was enzymatically derived for the first time into novel esters using lipase as biocatalyst. The reaction system of glycoside acylation was optimized, and the effect of solvent nature, concentrations of substrate and biocatalyst, and acyl donors' structure on the acylation was studied. In the optimal system, various structures of acyl donors, either natural or unnatural, including short alkyl acyl groups, long chain acyl groups and acyl donors with aryl group were connected to molecular backbone of the glycoside, forming various structures of novel glycoside esters.
- 社団法人日本生物工学会の論文
- 2008-07-25
著者
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Xu Jian-he
Laboratory Of Biocatalysis And Bioprocessing State Key Laboratory Of Bioreactor Engineering East Chi
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Yu Hui-Lei
Laboratory of Biocatalysis and Bioprocessing, State Key Laboratory of Bioreactor Engineering, East C
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Su Jin-Huan
Laboratory of Biocatalysis and Bioprocessing, State Key Laboratory of Bioreactor Engineering, East C
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Lu Wen-Ya
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
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Lin Guo-Qiang
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
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Yu Hui-lei
Laboratory Of Biocatalysis And Bioprocessing State Key Laboratory Of Bioreactor Engineering East Chi
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Lu Wen-ya
Shanghai Institute Of Organic Chemistry Chinese Academy Of Sciences
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Su Jin-huan
Laboratory Of Biocatalysis And Bioprocessing State Key Laboratory Of Bioreactor Engineering East Chi
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Lin Guo-qiang
Shanghai Institute Of Organic Chemistry Chinese Academy Of Sciences
関連論文
- Synthesis of Novel Salidroside Esters by Lipase-Mediated Acylation with Various Functional Acyl Groups(BIOCHEMICAL ENGINEERING)
- 24(I-10) Recent Development in the Synthesis and Bio-Screening of the Natural-Originated Compounds