P-TSA Catalyzed Facile and Efficient Synthesis of Polyhydroquinoline Derivatives through Hantzsch Multi-Component Condensation

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概要

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• A facile and efficient synthetic route to polyhydroquinolines has been developed via four-component condensation reactions of aldehydes, dimedone, ethyl acetoacetate and ammonium acetate in the presence of p-toluenesulfonic acid (p-TSA) catalyst in ethanol at ambient temperature through Hantzsch reaction. Simple work-up procedure, environmentally friendly, inexpensive and non-toxic catalyst, shorter reaction times along with excellent product yields are the significant features of this practical method.

• 公益社団法人日本薬学会の論文
• 2008-07-01

著者

• Mekala Raghu

  Department Of Chemistry Kakatiya University

• Cherkupally Sanjeeva

  Department Of Chemistry Kakatiya University

関連論文

• P-TSA Catalyzed Facile and Efficient Synthesis of Polyhydroquinoline Derivatives through Hantzsch Multi-Component Condensation

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