Phenolic Glycosides from Lindera fruticosa Root and Their Inhibitory Activity on Osteoclast Differentiation
スポンサーリンク
概要
- 論文の詳細を見る
Two new compounds were found in the phenolic glycosides isolated from the roots of Lindera fruticosa: 5-O-[β-D-apiofuranosyl-(1"→2')-O-β-D-xylopyranosyl]gentisic acid-7,5"-ester (3), named linderofruticoside A; and 5-O-[β-D-apiofuranosyl-(1"→3')-O-β-D-xylopyranosyl]gentisic acid methyl ester (4), linderofruticoside B. Two previously known phenolic glycosides were also identified: β-D-(3,4-disinapoyl)fructofuranosyl-α-D-(6-sinapoyl)glucopyranoside (1) and β-D-(3-sinapoyl)fructofuranosyl-α-D-(6-sinapoyl)glucopyranoside (2). Compounds 1 and 2 inhibited osteoclast differentiation in a dose-dependent manner at concentrations higher than 1.04μM and 0.132μM, respectively.
- 公益社団法人日本薬学会の論文
- 2008-05-01
著者
-
Baek Nam-in
Graduate School Of Biotechnology And Plant Metabolism Research Center Kyung Hee University
-
Kim Hong-hee
Department Of Cell And Developmental Biology College Of Dentistry Seoul National University
-
Chung Dae-kyun
Graduate School Of Biotechnology And Plant Metabolism Research Center Kyung Hee University
-
Song Myoung-chong
Graduate School Of Biotechnology And Plant Metabolism Research Center Kyung Hee University
-
Kim Ji-young
Graduate School Of Biotechnology And Inst. Of Life Sciences And Resources Kyunghee Univ.
-
Kim Ji-young
Graduate School Of Biotechnology And Plant Metabolism Research Center Kyung Hee University
-
NIGUSSIE Fikru
Faculty of Veterinary Medicine, Addis Ababa University
-
YANG Hye-Joung
Graduate School of Biotechnology and Plant Metabolism Research Center, Kyung Hee University
-
Yang Hye-joung
Graduate School Of Biotechnology And Plant Metabolism Research Center Kyung Hee University
-
Baek Nam-in
Graduate School Of Biotechnology And Inst. Of Life Sciences And Resources Kyunghee Univ.
-
Nigussie Fikru
Faculty Of Veterinary Medicine Addis Ababa University
-
Baek Nam-In
Graduate School of Biotechnology and College of Life Science, Kyung Hee University
関連論文
- The Methylene Chloride Fraction of Trichosanthis Fructus Induces Apoptosis in U937 Cells through the Mitochondrial Pathway(Molecular and Cell Biology)
- Inhibitory Effects of Agaricus blazei on Mast Cell-Mediated Anaphylaxis-Like Reactions(Pharmacology)
- Inhibition of Anaphylaxis-Like Reaction and Mast Cell Activation by Water Extract from the Fruiting Body of Phellinus linteus(Pharmacology)
- P-16 Antiinflammatory effect of Artemisia princeps(The 24th Annual Meeting of Medical and Pharmaceutical Society for WAKAN-YAKU)
- Shikonin, Acetylshikonin, and Isobutyroylshikonin Inhibit VEGF-induced Angiogenesis and Suppress Tumor Growth in Lewis Lung Carcinoma-bearing Mice
- Phenolic Glycosides from Lindera fruticosa Root and Their Inhibitory Activity on Osteoclast Differentiation
- 5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone : A Pancreatic Lipase Inhibitor Isolated from Alpinia officinarum(Pharmacognosy)
- Activation of Transcription Factors NF-κB and AP-1 by RANK
- Proteomic analysis of osteoclast lipid rafts : the role of the integrity of lipid rafts on V-ATPase activity in osteoclasts
- A Glycosidic Spinasterol from Koreana stewartia Promotes Procollagen Production and Inhibits Matrix Metalloproteinase-1 Expression in UVB-Irradiated Human Dermal Fibroblasts