冷血動物の心臓アレルギーの實驗的研究(第2報)

概要

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Frogs were sensitized with the same antigens as shown in report I, and after a period of 2〜3 weeks, the isolated frog's heart, which was fixed after Straub's method, was perfused with (1:100) and (1:500) solution of the mixture of rabbit myocardial phosphatid and fresh oxen sera. The amplitude of heart contraction was increased by the test solution in all sensitized groups, but not increased in the non-sensitized group. Lasting time of heart action after application of test solution was shorter in all sensitized groups than non-sensitized. From the results in report I and II, we were able to understand that frogs were sensitized with the mixture of phosphatid and serum consequently, as Maekawa's theory, even if dissimilar antigens introduced into them.
1955-02-20