迷走神經中に存する心臓促進神經に關する研究
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概要
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Although some investigators claim the presence of the vagal cardioaccelerator fibers, there still seems to be a considerable dispute in this problem. While Okinaka and his collaborators confirmed that the cardio-inhibitory fibers of the vagus nerve were localized in the caudal portion of the myelencephalic rootlets of the accessory nerve. Assuming that the probable vagal cardio-accelerator fibers run through the other portion of the rootlets, following experiments were carried out. First only the portion of the rootlets which contain the cardio-inhibitory fibers was cut on the right side intractanially in six dogs. About two weeks thereafter, when the cardio-inhibitory fibers selectively degenerated, cut vagus-stem rootlets of cut upper cervical vagosympathetic trunk were stimulated with faradic current. In five dogs moderate cardiac accelerations were demonstrated. Then in order to heighten the tonus of this vagal cardio-accelerator fibers, the right stellate ganglion was extirpated together with the section of the cardio-inhibitory rootlets on the right side. In this experiment seven dogs were used. In three, cardio-accelerations were found without the use of atropine. In one of them the acceleration was especially marked, before stimulation 4.5 beats per 5 seconds, after stimulation 10 beats per 5 seconds. In two of the remaining four, cardiac accelerations were observed only after the injektion of atropine. In these cases some portions of the rootlets which contain the cardio-inhibitory fibers were found intact at the autopsy. From these results, the presence of efferent cardio-accelerator fibers in the vagus nerve was definitely confirmed.
- 社団法人日本循環器学会の論文
- 1952-04-20