Cytotoxic Constituents from the Leaves of Cinnamomum subavenium

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概要

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• Two new butanolides, subamolide D (1) and subamolide E (2), and a new secobutanolide, secosubamolide A (3), along with 21 known compounds were isolated from the leaves of Cinnamomum subavenium. The structures of 1-3 were determined by spectroscopic analysis. Propidium iodide staining and cytometry analysis were used to evaluate the cell cycle progression of the treated SW480 cells and it was found that 1 and 2 caused DNA damage in a dose- and time-dependent manner.

• 公益社団法人日本薬学会の論文
• 2008-01-01

著者

• Kuo Soong-yu

  School Of Medicine And Health Sciences Fooyin University

• HSIEH Tian-Jye

  School of Medicine and Health Sciences, Fooyin University

• WANG Yau-Der

  Department of Medical Technology, Fooyin University

• LO Wen-Li

  School of Medicine and Health Sciences, Fooyin University

• HSUI Yen-Ray

  Division of Silviculture, Taiwan Forestry Research Institute

• CHEN Chung-Yi

  School of Medicine and Health Sciences, Fooyin University

• Lo Wen-li

  School Of Medicine And Health Sciences Fooyin University

• Wang Yau-der

  Department Of Medical Technology Fooyin University

• Hsui Yen-ray

  Division Of Silviculture Taiwan Forestry Research Institute

• Chen Chung-yi

  School Of Medicine And Health Sciences Fooyin University

• Hsieh Tian-jye

  School Of Medicine And Health Sciences Fooyin University

関連論文

• Cytotoxic Constituents from the Leaves of Cinnamomum subavenium

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