唾液腺腫瘍71症例の臨床統計

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Seventy-one patients treated for salivary gland tumors in our department during the past 25 years, from 1968 to 1993, were studied. This study included 33 males and 38 females with salivary gland tumors, indicating that tumors developed in females with a slightly higher frequency. The mean age of subjects was 46.2 years old for benign tumors and 56.3 for malignant. Of benign tumors, 25 were pleomorphic adenoma and one was a Warthin tumor. Of malignant tumors, 15 were adenoid cystic carcinoma, 13 mucoepidermoid carcinoma, 10 carcinoma in pleomorphic adenoma, 3 acinic cell carcinoma and the remainder were miscellaneous types. These tumors developed in the major salivary glands of 25 patients and in the minor salivary glands of 46 patients. Swelling was the most common symptom. Pain, ulcer, jaw trismus, and sensory nerve disturbance occurred with much greater frequency in cases of malignant tumors. Treatment results for previously untreated malignant tumors were analysed with respect to stage, treatment modality and histology: i) The 10-year cumulative survival rate was 95.0% for stages I and 11 and 23.0% for stages III and IV. ii) The surgical adjuvant therapy (S, S+C, S+C+R) had better prognosis than chemo-and radiotherapy(C+R). iii) The 5-year and 10-year cumulative survival rates were found to be as follows: mucoepidermoid carcinoma, 92.3% and 71.8% , respectively; adenoid cystic carcinoma, 83.0% for both intervals ; carcinoma in pleomorphic adenoma, 57.1% and 45.7%,respectively.
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唾液腺腫瘍71症例の臨床統計

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