A One-Pot Isoquinoline Synthesis by Cyclodehydrogenation of N-Benzyl-α-alkylaminoacetals with Chlorosulfonic Acid : Formation of 3-Alkylisoquinolines(Organic,Chemical)
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概要
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A direct preparation of fully aromatized 3-alkylisoquinolines (3e-p), was achieved by cyclodehydrogenation with chlorosulfonic acid of N-benzyl-α-alkylaminoacetals (2e-p) which were prepared by addition of Grignard reagent to N-benzyliminoacetals (1a-d).
- 公益社団法人日本薬学会の論文
- 1987-12-25
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関連論文
- A One-Pot Isoquinoline Synthesis by Cyclodehydrogenation of N-Benzyl-α-alkylaminoacetals with Chlorosulfonic Acid : Formation of 3-Alkylisoquinolines(Organic,Chemical)
- Formation of Isopavine by the Cyclization of N-[α-(3,4-Dimethoxybenzyl)-3,4-dimethoxybenzyl] aminoacetal with Chlorosulfonic Acid