Synthesis of Calf Thymosin β_4 Fragment 16-38 and Its Effect on the Impaired Blastogenic Response of T-Lymphocytes of a Uremic Patient with Pneumonia(Biological)

スポンサーリンク

概要

• 論文の詳細を見る

• Thymosin β_4 fragment 16-38, H-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-OH, was synthesized by a solution method, by assembling five peptide fragments followed by deprotection with 1 M trifluoromethane-sulfonic acid-thioanisole in trifluoroacetic acid. The synthetic tricosapeptide was tested for effect on the impaired blastogenic response of phytohemagglutinin-stimulated T-lymphocytes of a uremic patient with pneumonia. The synthetic tricosapeptide was found to have restoring activity, which was approximately equal in potency to that of our synthetic deacetyl-thymosin β_4.

• 公益社団法人日本薬学会の論文
• 1987-09-25

著者

• Sekino H

  Kidney Research Lab. Sendai Jpn

• Abiko T

  Kidney Research Lab. Sendai Jpn

• ABIKO TAKASHI

  Kidney Research Laboratory

• SEKINO HIROSHI

  Kidney Research Laboratory

関連論文

• Synthesis of Calf Thymosin β_4 Fragment 16-38 and Its Effect on the Impaired Blastogenic Response of T-Lymphocytes of a Uremic Patient with Pneumonia(Biological)

スポンサーリンク