Studies on Pyrimidine Derivatives. XXXIX. : Site-Selectivity in the Reaction of 5-Substituted and 4,5-Disubstituted Pyrimidine N-Oxides with Trimethylsilyl Cyanide(Organic,Chemical)

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概要

• 論文の詳細を見る

• The site-selectivity in the modified Reissert-Henze reaction of 5-substituted and 4,5-disubstituted pyrimidine 1-oxides with trimethylsilyl cyanide was examined. The reaction of 5-substituted 4-methoxypyrimidine 1-oxides with trimethylsilyl cyanide gave exclusively 2-pyrimidinecarbonitriles in good yields without exception. On the other hand, the other 5-substituted and 4,5-disubstituted pyrimidine 1-oxides gave mainly 6-pyrimidinecarbonitrilcs.

• 公益社団法人日本薬学会の論文
• 1987-08-25

著者

• YAMANAKA HIROSHI

  Pharmaceutical Institute, Tohoku University

• SAKAMOTO TAKAO

  Pharmaceutical Institute, Tohoku University

• Sagi M

  Tohoku Univ. Sendai Jpn

• Sakamoto T

  Showa Univ. Tokyo Jpn

• Sakamoto Takao

  Pharmaceutical Institute Tohoku University

• Yamanaka H

  Tohoku Univ. Sendai Jpn

• NISHIMURA SUMIKO

  Pharmaceutical Institute, Tohoku University

• SAGI MATAICHI

  Pharmaceutical Institute, Tohoku University

• Nishimura Sumiko

  Pharmaceutical Institute Tohoku University

• Yamanaka Hiroshi

  Pharmaceutical Institute Tohoku University

関連論文

• Isoxazole Derivatives as Centrally Acting Muscle Relaxants. II. : Synthesis and Structure-Activity Relationship of 3-Amino-N-(3-phenyl-5-isoxazolyl)propanamides
• Isoxazole Derivatives as Centrally Acting Muscle Relaxants. III. : Synthesis and Activity of Conformationally Restricted Analogs(Medeicinal Chemistry,Chemical)
• Studies on Pyrimidine Derivatives. XXXIX. : Site-Selectivity in the Reaction of 5-Substituted and 4,5-Disubstituted Pyrimidine N-Oxides with Trimethylsilyl Cyanide(Organic,Chemical)

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