Spectrophotometric Determination of Dopaminergic Drugs Used for Parkinson's Disease, Cabergoline and Ropinirole, in Pharmaceutical Preparations

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概要

• 論文の詳細を見る

• Simple and reproducible Spectrophotometric methods have been developed for determination of dopaminergic drugs used for Parkinson's disease, cabergoline (CAB) and ropinirole hydrochloride (ROP), in pharmaceutical preparations. The methods are based on the reactions between the studied drug substances and ion-pair agents [methyl orange (MO), bromocresol green (BCG) and bromophenol blue (BPB)] producing yellow colored ion-pair complexes in acidic buffers, after extracting in dichloromethane, which are spectrophotometrically determined at the appropriate wavelength of ion-pair complexes. Beer's law was obeyed within the concentration range from 1.0 to 35μg ml^<-1>. The developed methods were applied successfully for the determination of these drugs in tablets.

• 公益社団法人日本薬学会の論文
• 2007-04-01

著者

• Caglar Sena

  Istanbul University Faculty Of Pharmacy Department Of Analytical Chemistry

• ONAL Armagan

  Istanbul University, Faculty of Pharmacy, Department of Analytical Chemistry

• Onal Armagan

  Istanbul University Faculty Of Pharmacy Department Of Analytical Chemistry

関連論文

• Spectrophotometric Determination of Dopaminergic Drugs Used for Parkinson's Disease, Cabergoline and Ropinirole, in Pharmaceutical Preparations
• Analytical methods for the quantitative determination of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in biological samples

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