辺縁性歯周炎罹患歯肉のコレステロールエステルおよびトリグリセライドの構成脂肪酸について
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概要
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There is available a fair amount of the published literature on the relationship between the quantitative change of fatty matters in the human gingiva and cases of marginal periodontitis of a chronic nature. However, research efforts seen to be yet scanty that deal with cholesterolester and triglyceride which have come to draw our attention in recent years because of their physiological roles. In the present study, therefore, the author was concerned with a classification degrees of their symptoms and identified the main constituent fatty acids in cholesterolester and triglyceride in these different classes of the affected gingiva. By way of study material, use was made of a total of 40 subjects who consisted of 19 males and 21 females ranging 20 to 50 years in age, that had been diagnosed as cases of periodontitis in the Department of Periodontics, Nihon University School of Dentistry, and not suffering from any other disease except for some types of periodontitis, as determined by usual clinical tests including the previous history, oral examination. In terms of PMA indices, the study subjects were roughly classified into three groups of P.M and A. At the same time, the members of our faculty and those patients who were free from any gingival anomalies in the periodontal structure who had been consulted in the Department of Periodontology were used as controls. In extracting fatty matters from the gingiva, the method of FOLCH was followed in which cholesterolester and triglyceride were fractionated and were extracted by means of a thin-layer chromatography. Subsequently, the identification and quantitative measurments were made of fatty acids through gas chromatography. As a result of the study, the author arrived at the following conclusion. 1. The constituent fatty acids comprising cholesterolester and triglyceride were found to be myristic acid, palmitic acid, palmitoleic acid, oleic acid and linoleic acid. There was no appreciable difference in the kind of the fatty acids between normal subjects and various degree of the gingival inflamation in periodontal patient. 2. In terms of the percentage of fatty acids constituting cholesterolester, the leve of linoleic acid tended to increase, whereas palmitoleic acid revealed a tendency decrease. Moreover as compared with normal, P and M group on the contrary. 3. In terms of the percentage of fatty acids triglyceride, the level of oleic acid and linoleic acid tended to increase, whereas palmitic acid, palmitoleic acid and stearic acid revealed a tendency of decrease.
- 特定非営利活動法人日本歯周病学会の論文
- 1982-03-28