仔ラット頭蓋骨形成機転に及ぼすフッ素イオンの影響
スポンサーリンク
概要
- 論文の詳細を見る
It has been suggested that releasing of calcium from calvaria into culture medium was inhibited by sodium fluoride. In this study, the investigation was carried out for the concept about the influence of fluorine on new bone formation of rats by injecting sodium fluoride to the rats. The experimental animals were divided into three groups. Group 1 was treated with a single daily dose of 0.11mg sodium fluoride for 3 days beginning from the 3 rd day postnatally. Group 2 was treated with a single daily dose of 0.11mg sodium fluoride for 6 days also from the 3 rd day postnatally. The control group was administered without sodium fluoride. The rats' calvaria were obtained on the 9th day postnatally. The results were obtained as follows. 1. The daily body weight changes showed no significant differances among the 3 groups. 2. The fluorine that deposited in every mg tissus of rats' calvaria showed a 0.46±0.02μg in group 1, a 0.65±0.02μg in group 2 and a 0.011±0.001μg in control group. 3. The influence of fluorine on radio-active calcium in every mg dry tissus of calvaria of rats showed a 39370.07±198.42 DPM in group 1 and it was approximately 2.62% ^<45>CaCl_2 level increase as compared with control group. In group 2, it showed a 40914.09±202.27 DPM, and this was approximately 6.65% ^<45>CaCl_2 level increase as compared with a 38363.93±195.87 DPM radio-active calcium of control group. 4. The histological findings of the sagittal suture showed marked proliferation of osteoblasts, fibroblasts and collagen fibers in group 1 and group 2 as compared with the control group. With PAS and toluidine blue stainnigs group 1 and group 2 showed more marked positive reaction than control group. The positive reaction was noted especially around the osteoblasts and the fibroblasts and was noted diffusely in the newly formed osteoid. 5. The electromicroscopic findings of the sagittal suture showed prominent proliferation of collagen fibrils and prominent bone matrix formation in group 1 and 2 as compared with control group. The findings were more prominent in group 2 than in group 1. 6. According to the X-ray findings, the diameter of Haversian canals showed a tendency of narrowing in group 1 and group 2 as compared with control group. The areas between the parietal and the visceral laminae showed a remarkable tendency of increasing radio-opacity in group 1 and 2 as compared with control group and that in group 2 was more remarkable than in group 1. It is noted that the above results present increase of quantity of calcification and new bone formation on the sagittal suture according to the administration of sodium fluoride.
- 特定非営利活動法人日本歯周病学会の論文
- 1981-03-28
著者
関連論文
- 37.実験的Progeria-like Syndromeと外傷性咬合負荷による歯槽骨の変化 : 2.フッ素F-含有飲料水で飼育したときの歯槽骨内カルシウムの変動と組織変化(第22回 春季日本歯周病学会)
- 慢性剥離性歯肉炎の臨床例
- 歯周ポケット測定法に対する2〜3の検討 : 一般講演要旨
- 脈動性水流装置の水圧が歯肉の物理的性質に及ぼす影響(第II報)
- ラット胎児頭蓋骨吸収に対するFイオンの効果(第4報) : 一般講演要旨
- 脈動性水流装置(Pulsating water pressure)の水圧が歯肉の物理的性質に及ぼす影響 : 一般講演要旨
- 2.ラットの胎児頭蓋骨吸収に対するFイオンの効果 : 第2報 ^Caおよびin vitroによる検討(第2回 日本歯周病学会例会一般講演要旨)
- 21.ラット胎児頭蓋骨吸収に対するFイオンの効果(7)(第21回 春季日本歯周病学会)
- 32.ラット胎児頭蓋骨吸収に対するFイオンの効果(6)(第20回 秋季日本歯周病学会)
- 32.ラット胎児頭蓋骨吸収に対するF^-の効果EMX-2Aによる線分析(一般講演要旨,第22回 秋季日本歯周病学会)
- Hemisectionを行なった患者の遠隔成績について : 一般講演
- ラット胎児頭蓋骨吸収に対するFイオンの効果 : 一般講演
- Hemisectionを行った患者の遠隔成績について
- 歯周病患者にナイトガードを使用したときのナイトガードと歯の歪みについて : 一般講演
- 30.歯周病患者にナイトガードを使用したときのナイトガードと歯の歪みについて(第2回 日本歯周病学会例会一般講演要旨)
- 5.脈動性水流装置(Pulsating water pressure)の物理的性質(第1報)
- 5.ラットの歯槽骨を指標としたカルシウムのフィードバック機構に及ぼすFイオンの検討(第16回 日本歯周病学会総会一般講演要旨)
- 3.仔ラット頭蓋骨形成時期におけるLysosomal emzymeの役割(一般講演要旨,第23回 秋季日本歯周病学会)
- 仔ラット頭蓋骨形成機転に及ぼすフッ素イオンの影響