多細胞生物の再帰的増殖と細胞タイプ多様性の両立条件

概要

論文の詳細を見る
The development of a multicellular organism is a dynamic process. With the increase of the cell number, starting from one or a few cells, cells are differentiated with different compositions. These differet types of cells form an ordered pattern. It is rather surprising that differentiation in cell types and formation of controlled patterns are compatible, because the former gives morphogenetic diversification whereas the latter implies recursive production of a cell ensemble, reducing individual differences. We studied this problem by taking a simple cell model with intracellular reaction dynamics of chemical concentrations, cell-cell interactions, and increase in cell numbers. We show that, by starting from an initial object consisting of both the cell type with diverse chemicals and the differentiated cell type, the recursive production of a multicellular organism with morphogenetic diversity is possible.
日本生物物理学会の論文
2007-01-25