Investigation of optimal transmission mode for high contrast blood flow image obtained by subharmonic imaging

概要

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It is known that the second harmonic and subharmonic components, the frequencies of which are twice and one half of the fundamental frequency, are included in echoes from contrast agents. An imaging method, which employs a second harmonic, is widely used in medical diagnosis. On the other hand, subharmonic are expected to provide a higher contrast between biological tissues and blood flow because echo signals are generated only from blood containing the contrast agents. However, the subharmonic component echo signal power from contrast agents is relatively low. This has resulted in little progress in the field of subharmonic imaging. We have reported a new imaging method using transmitted waves which include two frequency components to enhance subharmonic echo signals. In this study, we investigated an optimal transmission mode and the relationship between subharmonic generation and amplitude ratio of two frequency components, 0.85 MHz and 3.4 MHz, in the transmitted wave by a simulation using RPNNP (Rayleigh-Plesset-Noltingk-Neppiras-Poritsky) model. As a result, the subharmonic components were generated effectively when we set the amplitude ratio of 0.85 MHz as 50%.
社団法人電子情報通信学会の論文
2007-01-19