Modulations of Immune Functions and Oxidative Status Induced by Noise Stress
スポンサーリンク
概要
- 論文の詳細を見る
Noise has long been realized as an environmental stress causing physiological, psychological and behavioral changes in humans. The aim of the present study was to determine the effect of acute or chronic noise stress on both cellular and humoral immune responses and oxidative status. BALB/c mice were exposed to 90dB (A) white noise 5 h per day for either 3 d or 4 wk. Hormone levels, splenic lymphocyte proliferation, lymphocyte subsets in spleen and thymus, serum antibody and oxidative status were determined. A 3-d exposure to noise stress resulted in increased hormone levels, splenic lymphoproliferation and serum IgM. On the other hand, a 4-wk exposure to noise stress caused a reduction of splenic lymphoproliferation, splenic CD4^+ cells and serum IgG, but hormone levels and urinary 8-hydroxy-2' deoxyguanosine (8-OHdG) were increased. These results imply that acute exposure to noise stress may enhance immune responses, whereas chronic exposure to noise stress may suppress both cellular and humoral immune functions. The effect of noise stress on immune functions may be related to neuroendocrine modulation and oxidative imbalance as well.
- 社団法人日本産業衛生学会の論文
著者
-
Zheng Kui-cheng
琉球大学 医学部地域環境医科学講座環境生態医学分野
-
Zheng Kui-cheng
Department Of Preventive Medicine
-
Zheng Kui-cheng
Department Of Environmental And Preventive Medicine Faculty Of Medicine University Of The Ryukyus
-
ARIIZUMI Makoto
Department of Environmental and Preventive Medicine, Faculty of Medicine, University of the Ryukyus
-
Ariizumi Makoto
Department Of Environmental And Preventive Medicine Faculty Of Medicine University Of The Ryukyus
関連論文
- Analysis of p53 and K-Ras Gene Mutations in Patients with Chronic Bronchitis Using Laser Capture Microdissection Microscope and Mutation Detection
- Modulations of Immune Functions and Oxidative Status Induced by Noise Stress
- Interleukin-4 and Interleukin-5 Expression in Mice Exposed to 2,4-Toluene Diisocyanate
- The Need for High Priorities in Preventive Health Care Administrations in Both Developed and Developing Countries
- Cytokine Profiles in Airways of Rats Exposed to Toluene Diisocyanate
- Potassium Excretion in Healthy Japanese Women Was Increased by a Dietary Intervention Utilizing Home-Parcel Delivery of Okinawan Vegetables
- Cytokine Production by Splenocytes and Thymocytes in Mice after Intranasal Exposure to Toluene Diisocyanate
- Eosinophil Infiltration in Airways of Mice Exposed to Toluene Diisocyanate