Expression of Stage-Specific Genes during Zygotic Gene Activation in Preimplantation Mouse Embryos(Developmental Biology)
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概要
- 論文の詳細を見る
The expression of mouse two-cell stage specific genes was studied using the modified DDRT-PCR method, which overcame the paucity of the experimental materials of preimplantation embryos. Embryo tissues equivalent to that of four blastomeres are sufficient for amplification of target genes as visualized using polyacrylamide gel. Sequence analyses and reverse Northern blots indicate that the genes of ATPase 6 and Ywhaz are expressed specifically in two-cell embryos. ATPase 6 is essential for one-cell to two-cell transition and plays an important role in establishment of oxidative phosphorylation, while Ywhaz is related to initiating cellular communication system.
- 社団法人日本動物学会の論文
- 2003-11-25
著者
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Zhang Jianke
Department Of Microbiology And Immunology Kimmel Cancer Center Jefferson Medical College Thomas Jeff
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Li Wenyong
Institute of Genetics and Developmental biology, Chinese Academy of Sciences
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Yu Weidong
Institute of Genetics and Developmental biology, Chinese Academy of Sciences
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Liu Guisheng
Institute of Genetics and Developmental biology, Chinese Academy of Sciences
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Chen Qingxuan
Institute of Genetics and Developmental biology, Chinese Academy of Sciences
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Yu Weidong
Institute Of Genetics And Developmental Biology Chinese Academy Of Sciences:graduate School Of The C
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Liu Guisheng
Institute Of Genetics And Developmental Biology Chinese Academy Of Sciences
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Chen Qingxuan
Institute Of Genetics And Developmental Biology Chinese Academy Of Sciences
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Li Wenyong
Institute Of Genetics And Developmental Biology Chinese Academy Of Sciences:graduate School Of The Chinese Academy Of Sciences:department Of Biology Fuyang Teachers College
関連論文
- Mammalian nitrilase 1 homologue Nit1 is a negative regulator in T cells
- Expression of Stage-Specific Genes during Zygotic Gene Activation in Preimplantation Mouse Embryos(Developmental Biology)