A CPG Component LE Generates Depolarization of Buccal Neurons by Producing Constant Plateau Potentials During Feeding Responses of Aplysia kurodai(Neurobiology)

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概要

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• In the buccal ganglia of Aplysia kurodai we have identified neurons (here termed LE neurons, or LE) producing plateau potentials lasting several seconds by application of short depolarizing currents. Results obtained from experiments using various bath solutions suggest that generation of these plateau potentials may be an endogenous property of LE. Application of various intensities or lengths of depolarizing currents induced in LE almost constant plateau potentials with fixed duration and depolarizing size. LE spikes produced monosynaptic EPSPs in the ipsilateral multiaction neuron (MA) and the jaw-closing motor neuron (JC) in the buccal ganglia. Conversely, MA spikes produced monosynaptic IPSPs in LE. There was electrical coupling between LE and both MA and JC. During the feeding-like response elicited by electrical stimulation of the nerve, LE showed rhythmic depolarization almost simultaneously with MA and JC, and firing on the plateau potentials occurred during the period of JC firing, the later phase of radula retraction. Hyperpolarization of LE during the feeding-like response suppressed generation of plateau potentials, though rhythmic small depolarization was still induced. During LE hyperpolarization, the duration of the depolarization of MA and JC was shortened. These results suggest that LE may be an element of the feeding CPG circuit and may contribute to part of the depolarization of MA and JC by generating constant plateau potentials during the feeding response, though LE may not have rhythmgenerating ability.

• 社団法人日本動物学会の論文
• 2006-07-25

著者

• Nagahama Tatsumi

  Department of Biology, Faculty of Science, Kobe University

• Nagahama Tatsumi

  Department Of Biophysics Faculty Of Pharmaceutical Science Toho University

• Nagahama Tatsumi

  Department Of Biology Faculty Of Science Kobe University

• Kinugawa Aiko

  Department of Life Science, Graduate School of Science & Technology, Kobe University

• Kinugawa Aiko

  Department Of Life Science Graduate School Of Science & Technology Kobe University

関連論文

• Modulation of a Feeding Neural Cicuit by Mecroinjection of K^+ Channel Exprssion Genes into a Single Identified Nueron in Aplysia kurodai(Neurobiology)
• Calcium Imaging for Detection and Estimation of Spike Activities in Aplysia Neurons(Physiology)
• A CPG Component LE Generates Depolarization of Buccal Neurons by Producing Constant Plateau Potentials During Feeding Responses of Aplysia kurodai(Neurobiology)
• Functional transplant of photoactivated adenylyl cyclase (PAC) into Aplysia sensory neurons

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