Gene Rearrangements in Post-Chernobyl Thyroid Tumours

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概要

• 論文の詳細を見る

• The Chernobyl accident in 1986 offered the unique opportunity to study molecular genetic mechanisms of radiation-induced thyroid carcinomas. In these tumours we have investigated gene rearrangements along the MAP kinase pathway. In particular, we have analysed rearrangements of the RET proto-oncogene (RET/PTC) by RT-PCR and interphase fluorescence in situ hybridisation (FISH) and gene fusion of BRAF by interphase FISH on paraffin-embedded tissue sections.

• 長崎大学の論文

著者

• Horst Zitzelsberger

  Gsf-national Research Center For Environment And Health Institute Of Molecular Radiation Biology

• Zitzelsberger Horst

  Gsf-national Research Centre For Environment And Health Institute Of Molecular Radiobiology

• Gerhard Jackl

  Institute of Radiation Biology

• Geraldine Thomas.

  South West Wales Cancer Institute, Singleton Hospital

• Geraldine Thomas.

  South West Wales Cancer Institute Singleton Hospital

• Unger Kristian

  Institute of Radiation Biology

• Malisch Eva

  South West Wales Cancer Institute, Singleton Hospital

関連論文

• P4-24 Chromosome rearrangements in a cell line derived from a case of childhood papillary thyroid cancer (chPTC) with radiation history
• Gene Rearrangements in Post-Chernobyl Thyroid Tumours

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