Synthesis and Biological Evaluation of Novel Benzimidazol/Benzoxazolylethoxypiperidone Oximes(Medicinal Chemistry)
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概要
- 論文の詳細を見る
Some novel benzimidazol/benzoxazolylethoxypiperidone oximes were synthesized and their antibacterial activity against Staphylococcus aureus (NCIM-2492), Bacillus subtilis (NCIM-2439), Escherichia coli (NCIM-2345) and Pseudomonas aeruginosa (NCIM-2035) and antifungal activity against Candida albicans (NCIM-C27), Candida-6 (NCIM-C27), Candida-51 (NCIM-C27), Aspergillus niger (NCIM-590) and Aspergillus flavus (NCIM-539) have been evaluated. Compounds 26 and 27 exerted potent in vitro antibacterial activity against Bacillus subtilis, Escherichia coli and Staphylococcus aureus while compounds 26, 29 and 30 exhibited potent in vitro antifungal activity against Candida albicans, Candida-51, and Aspergillus niger.
- 公益社団法人日本薬学会の論文
- 2006-01-01
著者
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Aridoss Gopalakrishnan
Department Of Chemistry Annamalai University
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Ramalingan Chennan
Department Of Chemistry Annamalai University
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Balasubramanian Srinivasan
Department Of Chemistry Annamalai University
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Parthiban Paramasivam
Department Of Chemistry Annamalai University
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KABILAN Senthamaraikannan
Department of Chemistry, Annamalai University
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Kabilan Senthamaraikannan
Department Of Chemistry Annamalai University
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- Synthesis and Biological Evaluation of Novel Benzimidazol/Benzoxazolylethoxypiperidone Oximes(Medicinal Chemistry)