Genomic DNA sequences of non GT-AG introons in human mRNA genes

概要

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We searched human genome DNA sequences in the DDBJ/GenBank/EMBL for introns of mRNA genes which do not conform to the GT-AG rule, and collected 5791 fragments which do not form exon parts. Of these 159 are not of GT-AG form. Then we eliminated 19 because of non introns that were yielded by clerical error, frameshift, edition policy, and so on. Major part (94) of the 140 remaining sequences can be considered also to be GT-AG forms with alternative interpretation. There are several mRNAs carrying more than one intron where not GT-AG forms but non-GT-AG ones are chosen. This suggests easy usage of easy selection, even when there is more than one candidate, by easy computer software to infer an intron sequence as the logical difference between a gene and its corresponding cDNA.
山形大学の論文
2005-02-15