Two New Triterpenoid Saponins Isolated from Polygala japonica

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概要

• 論文の詳細を見る

• Bioassay guided investigation of whole parts of Polygala japonica afforded two new triterpenoid saponins, characterized as 3-O-β-D-glucopyranosyl medicagenic acid 28-O-{β-D-xylopyranosyl(1→4)-[β-D-apiofuranosyl (1→3)]-α-L-rhamnopyranosyl(1→2)-β-D-glucopyranosyl} ester (1), 3-O-β-D-glucopyranosyl 2-oxo-olean-12-en-23, 28-dioic acid 28-O-{β-D-xylopyranosyl(1→4)-[β-D-apiofuranosyl(1→3)]-α-L-rhamnopyranosyl(1→2)-β-D-glucopyranosyl} ester (2), together with four known triterpenoid saponins (3-6). Their structures were elucidated by spectroscopic and chemical methods. Saponins 3, 4 and 5 showed significant anti-inflammation effects on carrageenan-induced acute paw edema in mouse.

• 公益社団法人日本薬学会の論文
• 2006-12-01

著者

• Yu Boyang

  Department Of Traditional Chinese Prescription China Pharmaceutical University

• Zhu Danni

  Department Of Traditional Chinese Prescription China Pharmaceutical University

• Yu Boyang

  Department Of Complex Prescription Of Tcm China Pharmaceutical University

• Gao Jie

  Department Of Computer Science University Of Tsukuba

• WANG Honglan

  Department of Traditional Chinese Prescription, China Pharmaceutical University

• GAO Tie

  Department of Traditional Chinese Prescription, China Pharmaceutical University

• Gao Tie

  Department Of Traditional Chinese Prescription China Pharmaceutical University

• Wang Honglan

  Department Of Traditional Chinese Prescription China Pharmaceutical University

• Yu Boyang

  Department Of Chinese Medicinal Prescription China Pharmaceutical University

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