Major Metabolites of Zolpidem : Expeditious Synthesis and Mass Spectra

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概要

• 論文の詳細を見る

• An expeditious route to the two major metabolites of Zolpidem-and readily applicable to the synthesis of the drug-was established via a cyclization reaction between a 2-aminopyridine and a suitable α-bromoace-tophenone. The structures of the target compounds were confirmed from a 2D ^1H-^<15>N NMR correlation. Their mass spectra contribute to a reliable toxicological identification of the drug in the case of drug-facilitated crimes.

• 公益社団法人日本薬学会の論文
• 2006-09-01

著者

• HOUSSIN Raymond

  Institut de Chimie Pharmaceutique Albert Lespagnol, EA 2692, Universite de Lille 2

• Henichart Jean-pierre

  Institut De Chimie Pharmaceutique Albert Lespagnol

• KLUPSCH Frederique

  Institut de Chimie Pharmaceutique Albert Lespagnol

• HUMBERT Luc

  Laboratoire de Toxicologie et Genopathies, Hopital A. Calmette, CHRU

• IMBENOTTE Michel

  Laboratoire de Toxicologie, Faculte des Sciences Pharmaceutiques et Biologiques

• LHERMITTE Michel

  Laboratoire de Toxicologie et Genopathies, Hopital A. Calmette, CHRU

• Houssin Raymond

  Institut De Chimie Pharmaceutique Albert Lespagnol

• Humbert Luc

  Laboratoire De Toxicologie Et Genopathies Hopital A. Calmette Chru

• Imbenotte Michel

  Laboratoire De Toxicologie Faculte Des Sciences Pharmaceutiques Et Biologiques

• Lhermitte Michel

  Laboratoire De Toxicologie Et Genopathies Hopital A. Calmette Chru:laboratoire De Toxicologie Facult

関連論文

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• Major Metabolites of Zolpidem : Expeditious Synthesis and Mass Spectra

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