A Method for Quantitative Determination of Furanocoumarins in Capsules and Tablets of Phytochemical Preparations

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概要

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• A method for sample preparation and analysis by high-performance liquid chromatography with UV detection (HPLC-UV) was developed for analysis of psoralen, bergapten and 5-[3-(4, 5-dihydro-5, 5-dimethyl-4-oxo-2-furanyl)-butoxy]-7H-furo[3-2-g][1]benzopyran-7-one in capsules and tablets employed in Brazil for certain illnesses. The linearity, accuracy, the inter- and intra-day precision of the procedure were evaluated. Analytical curves for furanocoumarins were linear in the range of 1.0-50.0μg/ml. The recoveries of the furanocoumarins in the products analyzed were 97.3-99.5%, and the percent coefficient of variation for the quantitative analysis of the furanocoumarins in the analyses was under 5%. For inter-equipment study gas chromatography (GC) was employed.

• 公益社団法人日本薬学会の論文
• 2006-04-01

著者

• Honda Neli

  Departamento De Quimica Universidade Federal De Mato Grosso Do Sul

• Cardoso Claudia

  Curso De Quimica Universidade Estadual De Mato Grosso Do Sul

• PIRES Adriana

  Departamento de Quimica, Universidade Federal de Mato Grosso do Sul

• Pires Adriana

  Departamento De Quimica Universidade Federal De Mato Grosso Do Sul

関連論文

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• A Method for Quantitative Determination of Furanocoumarins in Capsules and Tablets of Phytochemical Preparations
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