Synthesis, Characterization and in Vitro Cytotoxicity of Pentacoordinated Tin(IV) Complexes Derived from Aminoalcohols

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概要

• 論文の詳細を見る

• The synthesis of pentacoordinated Tin (IV) compounds derived from aminoalcohols is described. The compounds were characterized by IR, ^1H-, ^<13>C-, and ^<119>Sn-NMR, the mass spectrometry exhibits molecular ions corresponding to monomeric species. All compounds were evaluated for in vitro cytotoxic activities against five human tumor cell lines, U251 (human glioblastoma), PC-3 (human prostatic adenocarcinoma), K-562 (human chronic myelogenous leukemia), HCT-15 (human colorectal adenocarcinoma), MCF-7 (human mammary adenocarcinoma). The cytotoxic evaluation revealed that all compounds possess higher cytotoxic potency than that of the cisplatin, which was used as reference. Additionally, MT2 cells (human T-lymphocytes) were also evaluated.

• 公益社団法人日本薬学会の論文
• 2006-01-01

著者

• Gomez Elizabeth

  Instituto De Quimica-unam Circuito Exterior Ciudad Universitaria

• Gomez Elizabeth

  Instituto De Quimica Unam

• Ramirez-apan Teresa

  Instituto De Quimica Universidad Nacional Autonoma De Mexico; Circuito Exterior Ciudad Universitaria

• Ramirez-apan Teresa

  Instituto De Quimica-unam Circuito Exterior Ciudad Universitaria

• CONTRERAS-ORDONEZ Guadalupe

  Instituto de Quimica-UNAM, Circuito Exterior, Ciudad Universitaria

• Contreras-ordonez Guadalupe

  Instituto De Quimica-unam Circuito Exterior Ciudad Universitaria

• Ramirez-apan Teresa

  Instituto De Quimica Universidad Nacional Autonoma De Mexico

関連論文

• Heptacoordinate Tin(IV) Compounds Derived from Pyridine Schiff Bases : Synthesis, Characterization, in Vitro Cytotoxicity, Anti-inflammatory and Antioxidant Activity
• Crystal Structure of trans-Dibromobis(triphenylphosphine)platinum(II)
• Synthesis, Characterization and in Vitro Cytotoxicity of Pentacoordinated Tin(IV) Complexes Derived from Aminoalcohols

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