Cost-effectiveness analysis of influenza and pneumococcal vaccinations among elderly people in Japan

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During the periods of seasonal flu in 2003 and 2004, it was found that about 45percent of elderly people in Japan had been inoculated with influenza vaccines.Comparatively, however, the proportion of inoculation with pneumococcal vaccine wasonly 0.1 percent. Taking into account such incongruent proportions, this studyassesses health and economic benefits of vaccination strategies for both influenza andpneumonia particularly for the elderly population in Japan. To accomplish thisobjective, a cost-effectiveness analysis was conducted with the use of the Monte Carlosimulation based on the data from medical literature as well as from the publicorganizations, wherein three strategic patterns were delineated and compared (i) novaccination (ii) influenza vaccine only, and (iii) combined influenza with pneumococcalvaccines. The cost for one year of life saved by each strategy was compared with thescenario of no vaccinations. It was found that for 100,000 elderly people over 65 yearsof age in Japan, the cost-effectiveness ratio of influenza-only vaccination was 516,332Japanese yen per one year of life saved, while the combined vaccinations of influenzawith pneumococcal was 459,874 Japanese yen for the same benefit. The incrementalcost-effectiveness ratio of the strategies (iii) versus (ii) was 426,698 Japanese yen perone year of life saved for 100,000 people. Consequently it was indicated that thecombined vaccinations would be more cost-effective than the vaccination for influenzaonly.
神戸大学の論文

Cost-effectiveness analysis of influenza and pneumococcal vaccinations among elderly people in Japan

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