リアルタイムPCRによる腸管出血性大腸菌の検出およびロシアと日本における腸管出血性大腸菌感染症の比較

概要

論文の詳細を見る
Enterohemorrhagic Escherichia coli (EHEC; alternatively called Shiga toxin-producing Escherichia coli) belonging to a serotype, e.g., O157:H7 is an emerging cause of food-borne infections. It produces Shiga toxin, and causes hemorrhagic colitis and serious systemic disorders such as hemolytic uremic syndrome (HUS) with very negative prognosis. That's why rapid diagnosis is very important and it can be made by identification of Shiga toxin either by serological or DNA analysis. In this study, we investigated an EHEC mechanism of cell-infection by scanning electron microscopy. We also developed a rapid diagnosis method for EHEC with use of real time PCR assay, and compared cases (includeing treatment) of EHEC O157:H7 infections in Russia (Tula region) and Japan.
新潟大学の論文
2004-05-10